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This article was originally published on May 16, 2022, and updated on April 16, 2025. In high-pressure applications, managing pressures of 40,000 psi and above is critical for safety and efficiency. These environments pose significant challenges, such as extreme pulsation and vibration, which can lead to equipment failure and safety hazards. That's why ensuring your gauge is designed to withstand these conditions is so important. Since 1852, Ashcroft has been a trusted authority in pressure measurement, providing reliable solutions for demanding applications. Read this article to learn about common uses for ultra-high-pressure gauges, the standards they must follow for system and operator safety and considerations for selecting a pressure gauge for your needs. You will also be directed to additional resources to help you deepen your knowledge of relevant pressure gauge topics.