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In industries such as pharmaceutical, food, dairy and biotech, contamination is one of the greatest threats to product quality, safety and compliance. Even the smallest bacterial buildup in process connections can lead to costly downtime, product recalls and regulatory violations. The challenge is keeping the entire process environment ultra-clean and secure—especially at connection points where contamination can quickly occur. Tri-Clamp® fittings provide a proven solution, using a sanitary, crevice-free design that’s easy to clean, quick to assemble and fully compliant with industry regulations. As a leader in pressure and temperature instrumentation, Ashcroft has been trusted for over a century to deliver trusted instrumentation for critical process applications. Our expertise in hygienic measurement, combined with our conventional or inline style Tri-Clamp connections, helps manufacturers maintain sterility while keeping operations efficient. In this article, you’ll discover why Tri-Clamp connections are preferred for hygienic processes, how they outperform threaded fittings in sterile environments, and the best practices for selecting and installing gaskets to ensure long-term reliability.

This article was last updated on August 20, 2025. Whether you're monitoring hydrogen pressure, operating in high-vibration compressor systems, or designing for hygienic environments for sanitary food and beverage processing, reliable pressure measurement is essential to safety and process integrity. However, finding a pressure gauge that offers both durability and easy field serviceability can be difficult, especially in corrosive environments where access for instrument recalibration is critical. Ashcroft, a leading authority in pressure and temperature instrumentation, offers a solution designed to perform in challenging conditions and make field maintenance and OEM installations less challenging. Read this product review to learn about the Ashcroft® 8009S Pressure Gauge, an economical, all stainless-steel solution engineered to perform in challenging conditions. By the end of the article, you will know if this instrument is the right one for your needs.

This article was originally published on October 17, 2022, and updated on June 16, 2025. Precision and cleanliness are critical aspects of pharmaceutical and biotechnology manufacturing. From sterile production environments to aggressive chemical processes, pressure instruments must deliver consistent performance while supporting stringent regulatory requirements. Ashcroft has been manufacturing pressure instrumentation for pharmaceutical and biotechnology applications for generations. Over the past 10 years with the company, I have helped customers find the best solutions for their specific needs, drawing on trusted industry practices and proven instrumentation examples. Read this article to get a comprehensive overview of common instrument applications, industry challenges and primary considerations for selecting the product that will deliver the most accurate results. You will also find links to additional information that can help deepen your knowledge.

In sterile environments, including pharmaceutical manufacturing, food & beverage production and biotechnology, pressure gauges must undergo rigorous cleaning and sterilization to ensure hygienic compliance while maintaining process integrity and operational safety. Ashcroft is a globally recognized leader in pressure and temperature instrumentation. As experts in this field, it is our job to fully understand the requirements our products must meet for use in these highly regulated industries and answer customer questions to help them make informed decisions. The question that prompted this article was from a customer who wanted to know the different ways to keep their pressure instruments compliant with hygienic requirements. Read this article to learn what hygienic compliance means for sterile processes, who sets and enforces these standards and how three widely used cleaning methods—Clean-in-Place (CIP), Sterilize-in-Place (SIP) and autoclaving can help your systems prevent contamination. When you are done, you will have a better understanding of these processes, applications, benefits, and limitations as they relate to sanitary operations. You will also be directed to additional resources that can help you determine which instruments are best suited to keep your system running safely and efficiently in sterile environments.

This article was originally published on June 17, 2024, and updated on April 30, 2025. If you work in any industry that involves food, beverages, pharmaceuticals or biotechnology, your primary challenge is to implement and maintain strict sanitary control over your entire operation. This is your primary defense against product contamination and safeguarding public health. That means every aspect of your manufacturing process, including the equipment and instruments you use to keep your systems running smoothly, must also meet certain sanitary and hygienic standards. Ashcroft is a globally recognized leader in pressure and temperature instrumentation, so we understand the unique requirements our products must meet for use in these highly regulated industries. In fact, as a Product Leader for the company's sanitary product line, I am often asked for guidance during our customers' gauge selection process. In this article, you will learn more about the unique safety challenges of these highly regulated industries, the safety standards that are designed for public protection and some factors to consider when selecting the best sanitary gauge for your needs. When you are done reading, you will also be directed to additional resources to help deepen your knowledge of pressure gauges in general.

Industries such as food/beverage, paint applications, pharmaceutical and biotech have strict sanitary requirements to ensure that their products are manufactured in a clean and safe environment. Therefore, the pressure measuring instruments used in these applications must meet the same sanitary requirements.